Malignant melanoma of the oral caity
Keywords:
melanoma, oral cavity, rare, poor prognosisAbstract
Malignant melanoma of the oral cavity is a rare neoplasm and it is only 0.5 % of the malignant neoplasms of the oral cavity, and less than 10 % of all the malignant melanomas. The mean age for patients with oral melanoma is from 40 to 70 years; with a higher frequency between the 50 and 60 years. Pigmentation areas are frequently noted before diagnosis of this neoplasm. Some predisposing factors are mechanical traumas resulting from not well adapted prostheses, solar radiation, and chemicals. Although oral cavity melanomas can remain asymptomatic during a time, the clinical presentations include hemorrhage, ulceration and pain. Melanomas grow fast, generally in a vertical growth phase, with early invasion of bones and lymphatic nodes. The prognosis for patients with melanoma is poor with a 5-year survival rate. The election treatment is surgical. The early diagnosis, the recognition of the lesions for doctors and odontologists, and the biopsy of recent or old pigmentation areas in the mouth that they have some changes (ulceration, bleeding , etc.) will contribute to offer patients amore effective treatment and a higher survival rate. We will present the case study of a 78-year-old male patient with a tumor in the dental ridge surrounded by melanotic spots, which was diagnosed as invasive melanoma and confirmed with immunohistochemical techniques.
Downloads
References
Reséndiz-Colosia JA, Valenzuela-Flores AG, Gallegos-Hernández FJ, Flores-Díaz R, Barroso-Bravo S, Rodríguez-Cuevas VSA. Melanoma primario de la mucosa oral. Experiencia en un hospital de oncología. Cir Ciruj 2007;75: 257-62.
You-Jin Leea, Noriyuki Nagaia, Chong-Huat Siarb, Keisuke Nakanoa, Hitoshi Nagatsuka, Hidetsugu Tsujigiwa, Cheng-Hsiung Roan, Mehmet Gunduz. Angioarchitecture of Primary Oral Malignant Melanomas. Histochem Citochem 2002;50:1555-62.
Emmanouil K Symvoulakis, Dionysios E Kyrmizakis, Emmanouil I Drivas, Anastassios V Koutsopoulos, Stylianos G Malandrakis, Charalambos E Skoulakis, John G Bizakis. Oral mucosal melanoma: a malignant trap. Head & Face Medicine 2006;2: 7: 10. 1186 / 1746- -160X-2-7.
Lopez-Graniel CM, Ochoa-Carrillo FJ, Meneses-García A. Malignant melanoma of the oral cavity: diagnosis and treatment experience in a Mexican population. Oral Oncol. 1999;35:425-30.
Mustafa Göregen, Binali Cakur, Nesrin Gürsan, O. Murat Bilge. Primary malignant melanoma of the oral cavity. The Internet Journal of Dental Science. 2006; Vol 4 Number 1. 6. Shah J, Jain M. Malignant melanoma of the oral cavity: Report of two cases. J Oral Maxillofac Pathol 2006;10:24-7.
Nisha J, D'Silva ZK, Polverini PJ., Hanks CT, Paulino AF. Malignant Melanoma of the Oral Mucosa in a 17-Year-Old Adolescent Girl. Archives of Pathology and Laboratory Medicine. 2005;126:1110-13 .
López Chagin A ,Sardi J. Melanoma maligno de la cavidad bucal . Reporte de un caso.Home Ediciones 2003;41:35-41.
Hashemi Pour MS. Malignant melanoma of the oral cavity: A review of literature.Indian Journal of Dental Research 2008;19: 47-51
Infante Cossío P, García-Perla García A, Mayorga Jiménez F, Gutiérrez Pérez JL, Scherba J, Gavilán Carrasco F. Melanoma maligno de la cavidad oral: Estudio de tres casos. Revista española de cirugía oral y maxilofacial: Publicación Oficial de la Sociedad Española de Cirugía Oral y Maxilofacial, ISSN 1130-0558, 1999; 21:287-93
Colella G, Faillace G, Santagata M, Tartaro GP. Case of primary malignant melanoma oral: Minerva Stomatol. 1998;47:535-40.
Cebrian Carretero JL, Chamorro Pons M, Montesdeoca N. Melanoma of the oral cavity. Review of the literature. Med Oral. 2001;6:371-5.
Eisen D, Voorhees J. Oral melanoma and other pigmented lesions of the oral cavity. J Am Acad Dermatol 1991;24: 527-37.
Villarreal Renedo, P.M. et al. Tratamiento de los melanomas cutáneos de la cabeza y el cuello: Estado actual. Rev Esp Cirug Oral y Maxilofac. 2005, 27:183-95.
Downloads
Published
Issue
Section
License
Copyright (c) 2020 Universidad Nacional de Córdoba

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The generation of derivative works is allowed as long as it is not done for commercial purposes. The original work may not be used for commercial purposes.