Sindrome de Ovario Poliquístico

Revisión de su fisiopatogenia

Autores/as

  • Carolina Fux Otta
  • Marta Fiol de Cuneo
  • Paula Szafryk de Mereshian

DOI:

https://doi.org/10.31053/1853.0605.v70.n1.20282

Palabras clave:

síndrome de ovario poliquístico, insulino resistencia, fisiopatogenia

Resumen

El síndrome de ovario poliquístico (SOP), la endocrinopatía ginecológica más frecuente en mujeres en edad fértil, se caracteriza por hiperandrogenismo, anovulación crónica y/u ovarios poliquísticos. A pesar de que su etiología permanece desconocida y que se han propuesto diferentes hipótesis, en la actualidad se jerarquiza a la insulino resistencia como la principal causante del síndrome y su implicancia en las alteraciones metabólicas. La hiperinsulinemia compensatoria contribuye al hiperandrogenismo por diferentes vías: estimulando la síntesis ovárica de andrógenos e inhibiendo la producción hepática de la globulina transportadora de hormonas sexuales. A partir del estudio del ambiente intrauterino, en los últimos años se ha propuesto que el SOP podría tener un origen in útero relacionado con la exposición prenatal a andrógenos. El objetivo del presente trabajo es revisar las principales mecanismos propuestos como causantes del síndrome.

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Citas

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Publicado

2013-03-13

Cómo citar

1.
Fux Otta C, Fiol de Cuneo M, Szafryk de Mereshian P. Sindrome de Ovario Poliquístico: Revisión de su fisiopatogenia. Rev Fac Cien Med Univ Nac Cordoba [Internet]. 13 de marzo de 2013 [citado 19 de abril de 2024];70(1):27-30. Disponible en: https://revistas.unc.edu.ar/index.php/med/article/view/20282

Número

Vol. 70 Núm. 1 (2013)

Sección

Revisiones de literatura

Licencia

Derechos de autor 2018 Universidad Nacional de Córdoba

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