Eosinophilic granuloma of cranial location: report of a case and bibliographic review

Authors

DOI:

https://doi.org/10.31053/1853.0605.v78.n1.30451

Keywords:

histiocytosis, langerhans-cell, pediatrics, temporal bone

Abstract

Introduction: Eosinophilic granuloma is an unusual benign disease that usually affects the pediatric population and young adults. It is the most benign of the diseases traditionally known as histiocytosis X that are now called Langerhans cell histiocytosis.

Clinical Case: Pediatric patient with a painful lump in the temporal region. The imaging tests carried out reveal the existence of an osteolytic lesion with an aggressive pattern compatible with eosinophilic granuloma. The patient underwent surgery with a conclusive definitive histological diagnosis of eosinophilic granuloma.

Discussion: Eosinophilic granuloma can affect one or multiple bones, of which the most frequent are the cranial bones, epiphyses of long bones and ribs, requiring individualized diagnosis and treatment strategies for optimal management and results, with surgical treatment of First choice.

Conclusion: Eosinophilic granuloma is an infrequent benign condition that requires a correct anamnesis and clinical examination of the patient, as well as the demonstration of the characteristic radiological images, allowing a generally accurate presumptive diagnosis to be reached that in most cases can be considered definitive.

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Author Biographies

  • Juan Ramon y Cajal Calvo, Lozano Blesa University Clinical Hospital. Saragossa. Spain

    Doctor Radiodiagnostic Service of the Lozano Blesa Clinical University Hospital. Saragossa. Spain

    Graduated in Medicine from the University of Zaragoza

    Master of Initiation to research in medicine. Zaragoza's University

  • Enrique Alvarez Arranz, Servicio Radiodiagnóstico. Hospital Clinico Universitario Lozano Blesa

    Optional Area Specialist. Interventionism Service. Lozano Blesa University Clinical Hospital.

    Licensed in medicine. University of the Basque Country Doctoral school. 

    Doctoral school. Zaragoza University of Medicine

  • Marta Zamora Lozano, Hospital Clinico Universitario Lozano Blesa. Zaragoza. España

    Medical Orthopedic Surgery Traumatology Service of the Hospital Clinico Universitario Lozano Blesa. Saragossa. Spain

    Graduated in Medicine from the University of Zaragoza

    Master of Initiation to research in medicine. Zaragoza's University

References

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3. Rojas CR, Garcia BC, Parra RD, Solar GA,Oyanedel QR, Diaz BF et al. Compromiso óseo en histiocitosis de células de Langerhans en el niño: estudio radiológico simple. Presentación clínica y diagnóstico radiológico. Rev Chil Radiol. 2005,11:222-8.

4. Huang W, Yang X, Wu Z, Huang Q, Xiao J, Yang M et al. Langerhans cell histiocytosis of spine: a comparative study of clinical imaging features, and diagnosis in children, adolescents and adults. Spine J. 2013;13:1108-17.

5. Gómez Ruiz C, Buxade-Marti I, Hinojosa Bareas G. Granuloma eosinófilo óseo. SEMERGEN. 2011;37:573-5

6. Angelini A, Mavrogenis AF, Rimondi E, Rossi G, Ruggieri P. Current concepts for the diagnosis and management of eosinophilic granuloma of bone. J Orthop Traumatol. 2017;18:83-90.

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8. Dong-Xiao N, Hui-tu N, An-zhou T,Ruo-ze C. Langerhans cell histiocytosis (histiocytosis X) of temporal bone. J Otol.2007;2:36-41.

Published

2021-03-12

Issue

Section

Case Report

How to Cite

1.
Ramon y Cajal Calvo J, Alvarez Arranz E, Zamora Lozano M. Eosinophilic granuloma of cranial location: report of a case and bibliographic review. Rev Fac Cien Med Univ Nac Cordoba [Internet]. 2021 Mar. 12 [cited 2024 Nov. 25];78(1):48-51. Available from: https://revistas.unc.edu.ar/index.php/med/article/view/30451

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