Orígenes de la Salud y la Enfermedad

Autores/as

  • Eduardo Cuestas Hospital Privado de Córdoba

Palabras clave:

biología del desarrollo, hipótesis de barker

Resumen

Presentar un nuevo campo del conocimiento, que estudia los orígenes de la salud y la  enfermedad a través del desarrollo evolutivo del ser humano, abordando conceptos, métodos  e estudio, aspectos éticos y diferentes perspectivas referidas a ésta área del saber. Material y  métodos: Revisión de la literatura, para obtener referencias pertinentes y actualizadas  relacionadas con el tema. Resultados: Los estudios recientes demuestran asociaciones entre  eventos ocurridos en fases tempranas del desarrollo somático y el aumento del riesgo para presentar enfermedades crónicas a lo largo de la vida, tales como diabetes, obesidad y  enfermedades cardiovasculares. Se han propuesto diferentes modelos para explicar esas  asociaciones, como la teoría del fenotipo frugal, la programación, las respuestas adaptativas  predictivas y el concepto de concordancia o contraste. Algunos de los posibles mecanismos  involucrados en estos procesos son: efectos del ambiente sobre la expresión génica, a través  e mecanismos epigenéticos; efectos de señales hormonales transmitidos al feto a través de  a placenta o al neonato por la leche materna. 

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Biografía del autor/a

  • Eduardo Cuestas, Hospital Privado de Córdoba
    Servicio de Pediatría y Neonatología.

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Cuestas E. Orígenes de la Salud y la Enfermedad. Rev Fac Cien Med Univ Nac Cordoba [Internet]. 2019 Oct. 9 [cited 2024 Dec. 19];64(3):73-86. Available from: https://revistas.unc.edu.ar/index.php/med/article/view/25506

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