Função glomerular e síndrome metabólica em adultos venezuelanos com fatores de risco cardiometabólicos tratados em um centro de atenção primária
DOI:
https://doi.org/10.31053/1853.0605.v76.n3.23677Palavras-chave:
síndrome metabólica, taxa de filtração glomerular, proteinúriaResumo
Introdução: A relação da síndrome metabólica (SM) e seus componentes com a taxa de filtração glomerular e proteinúria ainda não está amplamente elucidada. O objetivo foi associar a taxa de filtração glomerular estimada (TFGe) e proteinúria com a SM e seus componentes individuais em adultos com fatores de risco cardiometabólico, que atendidos em um centro de saúde pública localizada no município San Diego, Carabobo -Venezuela.
Métodos: Estudo descritivo-transversal (n = 176 pacientes). Peso, altura, circunferência da cintura, percentual de gordura corporal e pressão arterial foram medidos; foram determinada em soro glicose, creatinina, ureia, azoto da ureia, colesterol total, colesterol de lipoproteína de baixa (LDLc) e alta densidade (HDLc), triglicerídeos e hemoglobina glicada A1C em sangue total; a presença de proteinúria foi determinada em urina parcial,. A TFG foi estimada por equações e o índice de massa corporal (IMC) foi calculado.
Resultados: A frequência de SM foi maior em pacientes com doença renal crônica (TFGe <60 mL/min/m2), TFGe discretamente diminuída (60-89 mL/min/m2), hiperfiltração ou proteinúria. Os riscos de uma ligeira diminuição na TFGe e proteinúria foram significativamente associados à SM, glicose sérica alta e HDLc baixo, com e sem ajuste para sexo, idade e IMC. Quando ajustado para a condição diabética, o risco de proteinúria estava associado à SM e à hipertensão. O risco de hiperfiltração não foi associado à SM.
Conclusão: A redução de TGFe e proteinúria foram associaram à SM e seus componentes individuais. Outros estudos devem confirmar os resultados.
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