Seroprevalence of Chagas´Disease in older than 14 years old in rural Chaco areas of Santa Fe Province

Authors

  • Diego Mendicino Universidad Nacional del Litoral
  • Carlina Colussi Universidad Nacional del Litoral
  • Mariana Stafuza Ministerio de Salud de la Provincia de Santa Fe
  • Silvia Manattini Ministerio de Salud de la Provincia de Santa Fe
  • Sandra Montemaggiore Ministerio de Salud de la Provincia de Santa Fe
  • Marcelo Nepote Ministerio de Salud de la Provincia de Santa Fe

DOI:

https://doi.org/10.31053/1853.0605.v76.n1.21946

Keywords:

seroprevalence, chagas disease, Gran Chaco.

Abstract

Introduction. Chagas´Disease (CD) is endemic en Chaco Región. It is unknown the seroprevalence in population older than 14 years old from rural Chaco areas of Santa Fe Province. This study aimed to determine the seroprevalence of and socio-environmental factors associated with CD in inhabitants >14 years old of rural Chaco areas of Santa Fe, Argentina. Methods.  A cross-sectional study was conducted between 2010 and 2015, in people over 14 years old, in the rural districts of the Chaco region, in the North of Santa Fe Province, Argentina. Blood serology for Trypanosoma cruzi antibodies based on two serological tests, and a third in case of discordance, were analized. Semi-structured survey was administered. Association between CD and socio-environmental variables were analyzed using prevalence ratios with 95% confidence intervals. Results. A total of 749 individual were analyzed, with an average of 29.5 years. The seroprevalence was 24.70% (26.69% in women and 20.26% in men). Socio-environmental variables showed association with Trypanosoma cruzi seropositive. The seroprevalence was 7.83 times higher in the children of mothers who had not reached secondary education. Conclusions Chaco region of Santa Fe is endemic for CD, as well as other provinces of the Region. The low level of education is the more important conditioning for this endemic disease.

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Author Biographies

  • Diego Mendicino, Universidad Nacional del Litoral
    Doctor en Ciencias de la Salud. Centro de Investigaciones sobre Endemias Nacionales. Facultad de Bioquímica y Ciencias Biológicas.
  • Carlina Colussi, Universidad Nacional del Litoral
    Bioquímica. Centro de Investigaciones sobre Endemias Nacionales. Facultad de Bioquímica y Ciencias Biológicas.
  • Mariana Stafuza, Ministerio de Salud de la Provincia de Santa Fe
    Bioquímica. Red de Laboratorios.
  • Silvia Manattini, Ministerio de Salud de la Provincia de Santa Fe
    Bioquímica. Red de Laboratorios.
  • Sandra Montemaggiore, Ministerio de Salud de la Provincia de Santa Fe
    Bioquímica. Red de Laboratorios.
  • Marcelo Nepote, Ministerio de Salud de la Provincia de Santa Fe
    Magister en Administración de Salud. Programa Provincial de Control de la Enermedad de Chagas.

References

Rassi A Jr, Rassi A, Marin-Neto J. Chagas disease. Lancet. 2010;375:1388-402.

Ministerio de Salud de la Nación. Normas para el Diagnostico y Tratamiento del Chagas. Buenos Aires: Ministerio de Salud de la Nación; 2008 Oct. 26p.

de la Rosa E, Paglini-Oliva P, Prato LB, Benizio E, Triquell MF, Muñoz SE, et al. Early Detection of Chronic Asymptomatic Chagas Infection. Med Sci Monit. 2018;24:4567-4571.

Hotez PJ, Bottazzi ME, Franco-Paredes C, Ault SK, Periago MR. The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. PLoS Negl Trop Dis. 2008;2:e300.

Gaspe MS, Provecho Y, Cardinal MV, Fernandez M, Gürtler R. Ecological and sociodemographic determinants of house infestation by Triatoma infestans in indigenous communities of the Argentine Chaco. PLoS Negl Trop Dis. 2015;9(3):1-26.

Moretti E, Castro I, Franceschi C, Basso B. Chagas disease: serological and electrocardiographic studies in Wichi and Creole communities of Misión Nueva Pompeya, Chaco, Argentina. Mem Inst Oswaldo Cruz. 2010;105(5):621-626.

Sosa-Estani S, Dri L, Touris C, Abalde S, Dell'Arciprete A, Braunstein J. Transmisión vectorial y congénita del Trypanosoma cruzi en Las Lomitas, Formosa. Medicina (B Aires). 2009;69(4):424-430.

Mendicino D, Stafuza M, Colussi C, Achkar G, Garnero N, Manattini S, et al. Chagas pediátrico en áreas rurales de la Provincia de Santa Fe. Rev Argent Salud Publica. 2015;6(25):14-18.

Streiger M, Demonte M, Fabbro D, Del Barco M, Miglietta H, Denner S. Multicausalidad y evolución de la prevalencia de infección chagásica humana en la provincia de Santa Fe, en relación al riesgo de transmisión vectorial. En: Actualizaciones en artropodología sanitaria argentina. Serie Enfermedades Transmisibles. Buenos Aires: Fundación Mundo Sano; 2002. p. 221-231.

Streiger M, Bovero N. Indirect immunofluorescence reaction for the diagnosis of Chagas disease. Preservation of theimprints. Medicina (B Aires). 1980;Suppl 1:250-1.

Castellanos-Domínguez Y, Cucunubá Z, Orozco L, Valencia-Hernández C, León C, Florez A, et al. Risk factors associated with Chagas disease in pregnant women in Santander, a highly endemic Colombian área. Trop Med Int Health. 2016;21(1):140-148.

Gurtler RE, Segura EL, Cohen JE. Congenital transmission of Trypanosoma cruzi infection in Argentina. Emerg Infect Dis. 2003;9(1):29-32.

Moreno M, Moretti E, Basso B, Frias M, Catalá S, Gorla D. Seroprevalence of Trypanosoma cruzi infection and vector control activities in rural communities of the southern Gran Chaco (Argentina). Acta Trop. 2010;113:257-262.

Klein K, Burrone MS, Alonso JP, Ares LR, Martí SG, Lavenia A, et al. Estrategia para mejorar el acceso al tratamiento etiológico para la enfermedad de Chagas en el primer nivel de atención en Argentina. Rev Panam Salud Publica. 2017;41:e20.

Genero S, Zorzo L, Chaparro M. Impacto de un programa de educación sanitaria sobre los conocimientos básicos de la enfermedad de Chagas en una población del Noreste Argentino. Rev Fac Cien Med Univ Nac Cordoba. 2018;75(3):168-175.

Published

2019-02-27

Issue

Section

Originales Breves

How to Cite

1.
Mendicino D, Colussi C, Stafuza M, Manattini S, Montemaggiore S, Nepote M. Seroprevalence of Chagas´Disease in older than 14 years old in rural Chaco areas of Santa Fe Province. Rev Fac Cien Med Univ Nac Cordoba [Internet]. 2019 Feb. 27 [cited 2024 Nov. 20];76(1):47-51. Available from: https://revistas.unc.edu.ar/index.php/med/article/view/21946

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