Tumores de celulas de la granulosa: Análisis estructural y ultraestructural

Authors

  • Gladys Martellotto Universidad Nacional de Córdoba. Facultad de Ciencias Médicas
  • Silvia Frede Universidad Nacional de Córdoba. Facultad de Ciencias Médicas
  • Susana Ortíz Universidad Nacional de Córdoba. Facultad de Ciencias Médicas
  • Ernesto Hliba Universidad Nacional de Córdoba. Facultad de Ciencias Médicas

DOI:

https://doi.org/10.31053/1853.0605.v58.n1.37052

Keywords:

granulosa cell tumor, structural analysis

Abstract

These ovarian neoplasm derive from the ovarian stromal component constituting around the 5 tu 12% of ah ovarian tumors.
Objective: To examine the histopathological and ul trastructural morphol ogic characterist ic of the neoplastic ceils and the patognomonic elenient of these tumors: Cali Exner's Bodies

Materiales and inethods: The materials corresponded lo 2 women of 52 and 55 years. The siniomatology was abdominal tumor that went in mercase.
The materials were fractioned for the histopathological conventional study and for ultrastructural analysis. For this last one, they
were tixed in Karnovsky, rehix tu osmio and included in Araldita.
Resuits: by means uf the different observations it was determined in buth cases the nuclear atipia, indentations nucici and prorninent nucleohi. In one of the cases the presence of Bc,dics of Cahl-Exner vas detecied, and ultrastruciuraly vas compound by whirled fibrils and amorphous material. wiih dense slructures electron tu its around. It was interest the infihirated of plasmatic cells around the tumors celis. These neoplasms are of interesi due to their impredectible hehavicr and lo the hormonal production thai can origi nate ahterations in othcr organs of the genital apparatus.

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Author Biographies

  • Gladys Martellotto, Universidad Nacional de Córdoba. Facultad de Ciencias Médicas

    Cátedra de Patología 

  • Silvia Frede, Universidad Nacional de Córdoba. Facultad de Ciencias Médicas

    Cátedra de Patología Humana. Dpto de Bioquímica Clínica 

  • Susana Ortíz, Universidad Nacional de Córdoba. Facultad de Ciencias Médicas

    Cátedra de Ptología Humana , Dpto de Bioquímica Clínica 

  • Ernesto Hliba , Universidad Nacional de Córdoba. Facultad de Ciencias Médicas

    Cátedra de Patología Humana. Dpto de Bioquímica Clínica  

References

Abbas A, Lichman A, Pober II- Inmunologia Celular y. Molecular. Editorial Interamericana España. II edición. 1996

Baker TR, P.iver M: Etiology, bioiogy and cpidemio]ogy of ovarian cancer. Semin Surg Oncol:10: 224-228. 1994.

B]austein A: Pathology of the femaie ge- nital tract. Edit. Springer Virlag III Edíc. N. York Pág. 505-5 13. 1977

Crazrner DW : Factors affecting the association of contraceptive and ovarian- Cancer N. Engi. J. Mcd 307: 1407-1411.1982

Cotran R., Kumar y., Collins T. Patología Estructural y Funcional. VI Edicion. Me Graw Hill España. 2000 Clement P.; Young R.- Atlas of gyneco]ogic surgical pathology - 1 edición - Churchill Livingstone- Singapoie. Saunders Company. USA- Pág: 364- 392. 2000

Czernobilsky B., MoIl R. Desmosomal plaque associated vimentin filaments in human ovarian granulosa ccli tumors and various histologic patterns. Am.J Pathol 126: 476-486. 1987

Fox E Agrawal R: A clinical Pathologic Study of 92 cases of granulosa ccli tumor of the ovary with speciai reference of the factors. Cancer 35: 321-241. 1975

Gafney Eoin F, Majmuder B. Ovarian granulosa ccli tumors. Inmunochemical local ization of stradiol and ul raestructure with functional correlations. Obstet. Gynecol.61: 311-319. 1983

Gompel C.; Silverberg S. Pathology in gynecoiogy and obstetrics. 4 edición.. Pág. 358 —379. J.B. Lippincott Company. Philadelphia. 1994

il - Lack E, Perez Atayde A: Granulosa theca ccli tumors in premearchal girls. A clinical pathologic study of ten cases. Cancer 48: 1854-59. 1981

Piver M. Epidemiology and etiology of ovarian cancer. Semin.Oncol 18: 174-177. 1991

Roboy SJ. Emhrioiogy of thc female geni- tal tract. In Kurman R.(-ed) Blaustein'Pathoiogy of the Fcniaie genital Traci 4` cd New York, Springer —Vcrlarg Pág. 3-31. 1994

Rosa¡J. Ackerman's surgicai pathology. Vol I 3' edición. Mosby. New York. 1997 I5-Russcil P, Bannatyne P: Surgical Pathology of the ovarics . Edimburgh Churchill Livings Tome 1989

Sculiy R.; Young R.; Clement P. Atlas of tumor pathology. Jumors of the ovary, maidevelopcd gonads, fallopian tube and broad ligament. AFIP. Bethesda, Maryland. USA Pág. 169-188. 1998

Sternberg S. Diagnostic surgical pathology. Vol II . 3a edición. Rayen Press- New York. Pág. 2229- 2233. 1999

Young Rh, Dudley AG, Scuily RE: Granulosa Ccii —Scrtoh Leydig Cdl an unclassified sex cord stromal tumors assosiated with pregnancy. A Clinic- pathologicai analysis of thicnty six case. Gynecolo Oncol: 181: 181-205. 1984

Young Rl-!., Scully R.: Ovarian sex-cord Stroma! Tumours. Recent Progress. mt J Gynaecol Pathol 1:101. 1982

Yong RE, Dichesin GR, Sully RE' Juvenile granulosa ccli tumor of the ovary. A clinical athologic analysis of 125 cases. Am. J. Surg Pathol 8: 575-596. 1984

Young R: The ovary. En Sternergs Diagnostic Surgical Pathology New York Rayen Press. 1994

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Published

2001-11-30

Issue

Section

Original Papers

How to Cite

1.
Martellotto G, Frede S, Ortíz S, Hliba E. Tumores de celulas de la granulosa: Análisis estructural y ultraestructural . Rev Fac Cien Med Univ Nac Cordoba [Internet]. 2001 Nov. 30 [cited 2024 Dec. 19];58(1):117-23. Available from: https://revistas.unc.edu.ar/index.php/med/article/view/37052

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