Influence of capsular pseudoexfoliation syndrome on hearing loss

Authors

  • Juan Pablo Real Departamento de Farmacia. Facultad de Ciencias Químicas. UNC. UNITEFA
  • Vilma Campana 1. Cátedra de Física Biomédica. Facultad de Ciencias Médicas. UNC. 2. Cátedra de Física Biomédica. Medicina. UNLaR
  • Consuelo Luna Hospital Privado Universitario de Córdoba.
  • Luciana Acosta Hospital Privado Universitario de Córdoba
  • Mariana Coronel Hospital Privado Universitario de Córdoba.
  • Eduardo Gomez-Demmel Hospital Privado Universitario de Córdoba
  • Luis Ignacio Tartara Cátedra de Física Biomédica. FCM. UNC

DOI:

https://doi.org/10.31053/1853.0605.v77.n2.27861

Keywords:

exfoliation syndrome, hearing loss sensorineural, audiometry

Abstract

Introduction: Pseudoexfoliation Syndrome (PEX) is a genetic-inherited disorder, consisting of the deposition of elastin microfibers in intra and extraocular tissue. PEX is one of the most common identifiable secondary causes of glaucoma. Several studies have associated PEX with systemic conditions and the finding of fibrillar material in the structures of the inner ear, similar to that of pseudoexfoliation detected in the eye, has been described.

Objective: to compare audiometric levels in patients with and without ocular PEX. Materials and Methods: Retrospective case-control study. 48 medical records of patients who attended the ophthalmology service of the Private Hospital of Córdoba were selected between January 2015 and December 2017, between 59 and 75 years. They were divided into groups: controls (n = 22): without PEX and cases (n = 26): with PEX. The medical records of patients who underwent ophthalmological and audiometric studies were analyzed. For the statistical analysis, the Student's T test was used for independent and paired samples; in all cases a level of significance  ≤ 0.05 was considered.

Results: The percentage of hearing loss was 56.8% in the control group and 82.7% in the PEX group. The percentage disability in the group with PEX was greater in monaural (p = 0.0008) and biaural (p = 0.0307) hearing compared to patients without PEX.

Conclusion: Patients with ocular PEX showed a higher percentage of hearing loss, compared to those patients without ophthalmic evidence of PEX.

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Author Biographies

Juan Pablo Real, Departamento de Farmacia. Facultad de Ciencias Químicas. UNC. UNITEFA

Doctor en Ciencias Químicas. EgresadO de la FCQ-UNC. Profesor Asistente del  Departamento de Ciencias Farmacéuticas- FCQ - UNC. Becario Postdoctoral de la Unidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA)-CONICET.

Vilma Campana, 1. Cátedra de Física Biomédica. Facultad de Ciencias Médicas. UNC. 2. Cátedra de Física Biomédica. Medicina. UNLaR

Doctora en Ciencias Biológicas. Egresada de la FCEFyN-UNC. Profesora Adjunta de la Cátedra de Física Biomédica - FCM - UNC. Profesora Titular de la Cátedra de Física Biomédica - Medicina - UNLaR. Docente Investigadora de la UNC.

Consuelo Luna, Hospital Privado Universitario de Córdoba.

Consuelo Luna. Médica egresada UNC. Especialista en oftalmologia, título otorgado por Consejo de Médicos de la Provincia de Córdoba.

Luciana Acosta, Hospital Privado Universitario de Córdoba

Medica cirujana egresada UNC. Especialista en oftalmologia, título otorgado por la UNC. Especialista oftalmopediatria título otorgado por el ministerio de salud de la provincia de Cordoba

Mariana Coronel, Hospital Privado Universitario de Córdoba.

Médica egresada de Universidad Nacional de Tucumán. Especialista en oftalmología, título otorgado por consejo de Médicos de la provincia de Córdoba.

Eduardo Gomez-Demmel, Hospital Privado Universitario de Córdoba

Médico oftalmólogo. Doctor en Medicina. Jefe del Servicio de Oftalmologia del Hospital Privado Universitario de Córdoba.

Luis Ignacio Tartara, Cátedra de Física Biomédica. FCM. UNC

Médico Especialista en Oftalmología

Doctor en Medicina y Cirugía

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Published

2020-04-07

How to Cite

1.
Real JP, Campana V, Luna C, Acosta L, Coronel M, Gomez-Demmel E, Tartara LI. Influence of capsular pseudoexfoliation syndrome on hearing loss . Rev Fac Cien Med Univ Nac Cordoba [Internet]. 2020 Apr. 7 [cited 2024 Jul. 3];77(2):68-72. Available from: https://revistas.unc.edu.ar/index.php/med/article/view/27861

Issue

Vol. 77 No. 2 (2020)

Section

Original Papers

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