Spontaneous mesenteric hematoma associated to warfarin with surgical resolution

Authors

  • Jose Gabriel Yaryura Montero Sanatorio Allende
  • María Laura Petersen Sanatorio Allende. Cirugía general.
  • Mario Alberto Cafaro Sanatorio Allende. Cirugía general.
  • Roberto Dario Cardenas Villa Sanatorio Allende. Cirugía general.
  • Agustín Bianco Sanatorio Allende. Cirugía general.
  • Blanca Cardozo Dutra Sanatorio Allende. Cirugía general.
  • Jose Sebastian Garcia Sanatorio Allende. Nueva Córdoba. General Surgery.

DOI:

https://doi.org/10.31053/1853.0605.v76.n2.23472

Keywords:

hematoma, mesentery, anticoagulants, warfarin, surgical procedures, operative.

Abstract

Introduction: spontaneous mesenteric hematoma is rare. It has been described as a complication of prolonged anticoagulation, more often associated with warfarin. The standard diagnostic study is computed tomography. Therapeutics of this pathology is under discussion. It is known that the conservative treatment is carried out in stable hemodynamically patients with spontaneous mesenteric hematoma, leaving surgical treatment as an alternative for patients in shock. Our objective is present a case of an adult patient with spontaneous mesenteric hematoma in relation to the warfarin, surgically treated with good evolution. Clinical case: Patient of 67 years, female, with spontaneous mesenteric hematoma in relation to warfarin, with a history of replacement of the mitral biological valve with tricuspid plastic of more than 3 months, in daily controls due to mishandling of coagulation with oral anticoagulant; she consult for sudden abdominal pain, in the epigastric region, accompanied by gastric vomiting. Physical examination she presented abdominal defense and peritoneal reaction. Computed tomography of the abdomen and pelvis was requested, where mesenteric hematoma is reported. Because the patient presented signs of peritoneal irritation, emergency surgery was performed with segmental resection of the small intestine; with good postoperative evolution, being discharged on the fifth day. Pathological anatomy reports massive submucosal hemorrhage. Conclusion: in a patient with abdominal pain with signs of peritoneal irritation, alteration of International Normalized Ratio due to the use of warfarin, without a traumatic history, a spontaneous mesenteric hematoma should be suspected and surgical treatment should be considered.

Downloads

Download data is not yet available.

Author Biographies

Jose Gabriel Yaryura Montero, Sanatorio Allende

Residente de tercer año, de cirugía general en el Sanatorio Allende

María Laura Petersen, Sanatorio Allende. Cirugía general.

Residente de cuarto año de cirugía general. Sanatorio Allende

Mario Alberto Cafaro, Sanatorio Allende. Cirugía general.

Residente de cuarto año de cirugía general. Sanatorio Allende.

Roberto Dario Cardenas Villa, Sanatorio Allende. Cirugía general.


Residente de cuarto año de cirugía general. Sanatorio Allende.

Agustín Bianco, Sanatorio Allende. Cirugía general.

Sanatorio Allende. Cirugía general.

Blanca Cardozo Dutra, Sanatorio Allende. Cirugía general.

Residente de tercer año de cirugia general. Sanatorio Allende.

Jose Sebastian Garcia, Sanatorio Allende. Nueva Córdoba. General Surgery.

Surgeon. National University of Córdoba. Year 2006.
Specialist in General Surgery. National University of Córdoba. Year 2012.
Specialist in General Surgery. Medical Council of the Province of Cordoba. Year 2012.
Specialist in General Surgery. Argentine Association of Surgery. Year 2012. Medical Surgeon Certification.
Board of Certification of Medical Professionals. Year 2012
Fellowship in Colorectal Surgery. Cleveland Clinic Florida. Weston Florida, United States. Year 2013-2014.
Full Member of the Argentine Association of Surgery (MAAC). Year 2012.
Member of the American Society of Colon and Rectal Surgeons (MASCRS). Year 2014.
Adherent Member of the Surgery Association of Córdoba. Year 2013.

INTERESTS

Colorectal surgery laparoscopy benign and oncological.
Mini-invasive endoscopic Transanal Surgery (TAMIS).
Laparoscopic surgery of solid organs (spleen, adrenals).
General laparoscopic surgery (gallbladder, appendectomy, etc.).
Anorectal surgery (haemorrhoids, anal fissure, complex perianal fistulas, HPV.)
General surgery.

References

Bekheit M, AlaaSallam M, Khafagy P y cols. Non-traumatic intramural hematomas in patients on anticoagulant therapy: Report of three cases and overview of the literature.

Afr J Emerg Med. 2014; 4(4): e1–4.

Hirano K, Bando T, Osawa S y cols. Spontaneous mesenteric hematoma of the sigmoid colon associated with rivaroxaban: A case report. Int J Surg Case Rep. 2018; 44: 33–7.

Yolda? T, Erol V, Çal??kan C, Akgün E y cols. Spontaneous intestinal intramural hematoma: What to do and not to do. Ulus Cerrahi Derg. 2013; 29 (2): 72–5.

Hou S-W, Chen C-C, Chen K-C y cols. Sonographic diagnosis of spontaneous intramural small bowel hematoma in a case of warfarin overdose. J Clin Ultrasound. 2008; 36 (6): 374–6.

Uzun MA, Koksal N, Gunerhan Y y cols. Intestinal obstruction due to spontaneous intramural hematoma of the small intestine during warfarin use: a report of two cases. Eur J Emerg Med. 2007; 14 (5): 272–3.

Shikata D, Nakagomi H, Takano A y cols. Report of a case with a spontaneous mesenteric hematoma that ruptured into the small intestine. Int J Surg Case Rep. 2016; 24: 124–7.

Parker S, Thompson J. Spontaneous mesenteric haematoma; diagnosis and management. BMJ Case Rep. 2012.

Aguilar-Fernández I, Martínez-Ríos I, Gavilán-Carrasco J y cols. Spontaneous mesenteric hematoma of unknown origin. An Med Interna 2006; 23(6): 296–7.

Hassan I, Rasmussen T, Schwarze U y cols. Ehlers-Danlos Syndrome Type IV and a Novel Mutation of the Type III Procollagen Gene as a Cause of Abdominal Apoplexy. Mayo Clin Proc. 2002; Vol. 77.

De Brito P, Gomez M, Besson M y cols. Hématome mésentérique: rare complication d’un traitement anticoagulant oral au long cours. Ann Chir. 2006; 131(9): 529–32.

Ou-Yang C, Hsiao T, Chou Y y cols. Spontaneous intramural small-bowel hematoma due to a rare complication of warfarin therapy: Report of two cases. J. Acute Med. 2014; 4(1): 45–8.

Moftah M, Cahill R, Johnston S. Spontaneous sublingual and intramural small-bowel hematoma in a patient on oral anticoagulation. Gastroenterol Insights. 2012; 4(2): 17.

Sorbello M, Utiyama E, Parreira J y cols. Spontaneous intramural small bowel hematoma induced by anticoagulant therapy: review and case report. Clinics (Sao Paulo). 2007; 62 (6): 785–90.

Jimenez J. Abdominal pain in a patient using warfarin. Postgrad Med J.1999; 75(890): 747–8.

Askey J. Small bowel obstruction due to intramural hematoma during anticoagulant therapy, a non-surgical condition. Calif Med. 1966; 104(6): 449–53.

Published

2019-06-19

How to Cite

1.
Yaryura Montero JG, Petersen ML, Cafaro MA, Cardenas Villa RD, Bianco A, Cardozo Dutra B, Garcia JS. Spontaneous mesenteric hematoma associated to warfarin with surgical resolution. Rev Fac Cien Med Univ Nac Cordoba [Internet]. 2019 Jun. 19 [cited 2024 Jul. 17];76(2):118-20. Available from: https://revistas.unc.edu.ar/index.php/med/article/view/23472

Issue

Section

Case Report