Palavras-chave
sistema endocanabinóide
estresse
ansiedade
depressão
saúde psicoemocional
Como Citar
Resumo
Os ácidos graxos poliinsaturados “essenciais” (PUFAs) das famílias w6 e w3 devem ser ingeridos através dos alimentos. Esses lipídios são os precursores de muitas moléculas de intensa bioatividade, chamadas coletivamente de “eicosanóides” que incluem os endocanabinóides (ECB) ou canabinóides endógenos. Este artigo analisa os componentes do sistema ECB e as suas funções em condições de saúde e em situações de estresse crônico, depressão e ansiedade, circunstâncias habitualmente associadas. Os efeitos da administração exógena de PUFAs e a consequente modulação do sistema ECB também são descritos. Propõe-se que o sistema do ECB possa ser modificado favoravelmente pela manipulação exógena dos PUFAs presentes no corpo, através de modificações dietéticas. Isto poderia potencialmente facilitar la prevenção e gestão de perturbações do humor, particularmente estresse, depressão, ansiedade e perturbações semelhantes que afetam a saúde psicoemocional.
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