Palabras clave
trastornos mentales
enfermedades neurodegenerativas
deterioro cognitivo
Cómo citar
Resumen
El síndrome metabólico es una combinación de alteraciones metabólicas, con una prevalencia estimada en un 20-25% de la población mundial. Según la evidencia experimental, clínica y epidemiológica se asocia con los principales trastornos psiquiátricos, alteraciones en el sistema nervioso y enfermedades neurodegenerativas. La obesidad, que induce un estado inflamatorio crónico, y la insulinoresistencia parecen ser los principales procesos fisiopatológicos basales que llevan a progresiva neuroinflamación, daño en el tejido nervioso y deterioro cognitivo. Se proponen intervenciones terapéuticas simples como: la dieta, actividad física, mejora de la calidad del sueño y ciertos medicamentos con potenciales efectos neuroprotectores.
Citas
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