Indicaciones y contraindicaciones oncológicas del uso de hormonas en la menopausia

José Antonio Sarriá

doi:10.31053/1853.0605.v62.n2.27917

Autores/as

José Antonio Sarriá

DOI:

https://doi.org/10.31053/1853.0605.v62.n2.27917

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.

Resumen

Las expectativas de vida han cambiado ci manejo de la menopausia, etapa de la vida en la que la mujer presenta la mayor incidencia de cáncer. La terapia hormonal (TH) tiene en la actualidad indicaciones más acotadas y en particular en las pacientes que ya tuvieron cáncer. Las contraindicaciones oncológicas para el uso de TH son analizadas en relación a tumores hormono dependientes (endometrio y mama), a los con dependencia parcial (ovario y adenocarcinoma de cuello) y a los independientes (cuello,vulva y vagina).El cáncer colorectal, de alta mortalidad, se suponía protegido por TH, pero hoy no se puede confirmar esa observación. El aumento de incidencia y mortalidad del cáncer de maina es concluyente. La alta prevalencia de este tumor invita a ser cautelosos y advertidos en el diagnostico precoz en aquellas poblaciones mas expuestas. La TH combinada y por periodos de mas de 10 años demostró un incipiente incremento. Se esta en la búsqueda de hormonas selectivas que no estimulen los receptores en la mamay en el enclometrio y que actúen favorablemente sobre otras áreas.

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