Sarcopenia

is a clinical diagnosis possible?

Authors

  • Vanina Soledad Lerena Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín
  • Elizabeth Carolina Coronello Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín
  • Ilsen Catherine Torres Barrón Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín
  • Sabrina Paola Lucas Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín
  • Adriana Graciela Diaz Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín

DOI:

https://doi.org/10.31053/1853.0605.v81.n1.42334

Keywords:

sarcopenia, muscle strength, hand grip, muscle mass

Abstract

Introduction: Sarcopenia increases the risk of falls and fractures, as well as being related to various diseases and increased mortality. Different research groups propose different definitions that include the measurement of muscle mass by DXA and the assessment of hand grip strength through a hand dynamometer. However, these 2 instruments are not usually available in clinical practice. Our objective was to determine the diagnostic utility of 2 physical performance tests: gait speed and sit to stand test, as tools for the detection of patients with probable sarcopenia. A total of 706 women between 50 and 85 years of age were included and 376 of them completed the evaluation with the measurement of muscle mass. Anthropometric measurements were taken and physical performance was evaluated. We found that 26.1% registered a reduced gait speed while 55.3% presented alterations in performing the sit to stand test. The prevalence of sarcopenia ranged from 4.5% to 35% depending on the criteria used. Both tests showed a high negative predictive value (>70%) for the diagnosis of sarcopenia, while the sit to stand test also showed high sensitivity (>66%) for this diagnosis. We concluded that the implementation, in the clinical practice, of these easy and free tests would simplify the detection of patients with probable sarcopenia.

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Author Biographies

Vanina Soledad Lerena, Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín

Médica recibida de la Universidad Nacional del Litoral. Especialista en Clínica Médica. Especialista Universitaria en Endocrinología, Universidad de Buenos Aires. Experiencia: Médica en Sanatorio Finochietto e Instituto Argentino de Diagnóstico y Tratamiento, Buenos Aires. Actualmente: Médica endocrinóloga en Hospital de la Baxada Doctora Teresa Ratto, Paraná, Entre Ríos. Consultorios privados en Paraná, Entre Ríos. ORCID: 0000-0002-7913-265X

Elizabeth Carolina Coronello, Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín

Elizabeth Carolina Coronello: Médica recibida en la Universidad de La Plata. Especialista Universitaria en Endocrinología, Universidad de Buenos Aires. Experiencia: Médica del servicio de endocrinología, Hospital Lanari, Buenos Aires. Médica en Sanatorio Finochietto, clínica del sol, Instituto Taquini, Osecac, Rossi, Buenos Aires. Actualmente: Medical Science Liaison, Laboratorio Novo Nordisk. Consultorio privado Dr. Manavela, Buenos Aires. Disertante en curso modular de actualización clínica endocrinológica, Laboratorio Montpellier. ORCID: 0000-0001-6277-1220.

Ilsen Catherine Torres Barrón, Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín

Médica recibida de la Universidad Mayor San Francisco Xavier de Chuquisaca – Bolivia. Especialista Universitaria en Clínica Médica Universidad de Barcelo - SMIBA – AMA. Especialista Universitaria en Endocrinología Universidad de Buenos Aires. Magister en Diabetes y Metabolismo Universidad Rene Favaloro. Actualmente: Médica Endocrinóloga en Hospital Obrero Nro 6 "Jaime Mendoza" Sucre – Bolivia.

Sabrina Paola Lucas, Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín

Médica recibida en la Universidad de La Plata. Especialista Universitaria en   Endocrinología, Universidad de Buenos Aires. Magister en Osteología y metabolismo mineral de la  Universidad del Salvador. Actualmente, Jefe de la Sección de Densitometría de la División Endocrinología del Hospital de Clínicas José de San Martín, Universidad de Buenos Aires.

Adriana Graciela Diaz, Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas José de San Martín

Médica recibida de la Universidad del Salvador. Especialista Universitaria en Endocrinología, Universidad de Buenos Aires. Doctora en Medicina Interna de la Universidad de Buenos Aires. Magister en Osteología y Metabolismo Mineral Óseo de la Universidad del Salvador. Actualmente, Jefe de la Sección Osteopatías Medicas de la División Endocrinología del Hospital de Clínicas "José de San Martín", Universidad de Buenos Aires. ORCID: 0000-0002-9108-2288.

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Published

2024-03-27

How to Cite

1.
Lerena VS, Coronello EC, Torres Barrón IC, Lucas SP, Diaz AG. Sarcopenia: is a clinical diagnosis possible?. Rev Fac Cien Med Univ Nac Cordoba [Internet]. 2024 Mar. 27 [cited 2024 Jul. 20];81(1):83-95. Available from: https://revistas.unc.edu.ar/index.php/med/article/view/42334

Issue

Section

Original Papers