Alkaline phospatase activity in plasma of pregnant chagasic patients
DOI:
https://doi.org/10.31053/1853.0605.v55.n1.40337Keywords:
chagas disease, placental alkaline phosphatasc, pregnancyAbstract
lite linetic properties of plasma placental alLaline phosphauase patients \vith Chagas' disease vere siudied. When Cl.Mc vas used as auivatorthe sanie mercaSe of activ iv (1 7-20 0) vas lound in thc chagasic and noii chagasic groups. Fhe enzvnie was (101 inh ihited bv 1:. ion u an of uhe groups. No sign iflcant differences were deteeted betveen the 1\Vo groups (clmtrasic and non chaasic) when the enzvrne vas tieatcd vith inhibitors such as [DTA and L-phenvia lan ¡ nc. 1 lowever, whcn the CN ion
was used, the enzynie of the normal pregnant vonien hllowed a Michaelian curve. whcreas ¡u Ihe chagasic group a sigmoideal piot vas observed. [hus. the Hill cocfhcmentwas 1.1 for the normal uroup and over 1 .5 lr (he chagasic.
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