Estudio estructural comparativo de los blastomas gliales del Sistema Nervioso Central
DOI:
https://doi.org/10.31053/1853.0605.v56.n1.38733Keywords:
Gliomas, Silver irnpregnation, immunomarking for GPFA, histogenesis, CiassificationAbstract
The objective ofour work is tu compare 2 diagnostics methods and denionstrate the similarities of the ditferent Central Nervous
System (ilial Tumor Classifications. 1 mm unomarki ng tec h niques for gliofibrilar acid protein (GFAP), and special silver impregnations to compare the results acco rdi ng tu the last h i stogen clic interpretations were Lised.
95 Glionias were studied with heniatoxiline-eosine and silver techniques, and in 58 randomized selected cases the techniquetor GFAP was also used Both iriethods showecl the sanie results in the diagnosis of Glial Tuniors whose cells possess gliotibn Is: Glioepitelioma (Ependynionia), (3 lioblastomu, Astroblastoma, and Astrocytoina.
In the Oligodendrioglomas whose cells possess inicrotubules but not gliofibrils, 11-te silver tecliniques marked these cells and their
pi-olongitioiis while the technique for GFAP did not.
Regardi ng (iliomas, there are similarities by coniparing dic Del Río Ortega- Polak classilication with those ofthe \VHO and other authors. There are differences only in ihe "mimes" of sorne tumors or ni their histogenetic interpretation, which are not
substantial and are conhned to the "Polar Espongioblastorna'' and "Ghosarconia". Thercfore. ve think that the recongnitlon of the Del Río 1 Iortega-Poiak classification isjustilied.
Downloads
References
PolaK M: 13 lastomas del Sistema Nervioso Central y Periférico. Buenos Aires. Lopez Libreros Ed., 1966 Cejas H. - Piva J., Cejas A: Introducción a
las técnicas de inipregnaciór argéntica. Asoc Arg. de Pat. Cuaderno N' l , Santa Fe, 1981. Velazco M. Dahl D. Roessnian V., Uambetti P.: Immunohisioche-m¡cal local ization of the gl ial fibrillary acidic protein in human glial neoplasms. Cancer 45:484-94, 1980.
Del Río Hortega P.: Nomenclatura y Clasificación de los Tumores del Sistema Nervioso. Buenos Aires. Ed Lopez Etchegoyen, 1945.
Del Río Hortega P.: Anatomía microscópica de los tumores del sistema nervioso central Y periférico. Trabajo del [ab. de Histopat. N° 103, Madrid. Actas del Coner. lntei-nac. de Cancer, 1933.
Del Río Hortega R: Estructura y sistematización de los gliomas y paragliomas. Arch Esp (le Oncol, 2:411- 67 7. 932
Rubinstein U: Tumors of the Central Nervous Systcni. In: Atlas of Tumor Pathology. Armed l'orces lnstit of Patliology. Washington DC, Serie 2, Fase 6. 1972
Eng L. Rubinstein U : Contribution o] uumunohistocheniistry to diagnostic problems of human cerebral tumors. J Histocheni Cytochem, 26: 513-22, 1978
Del Río Flortega P: El método del carbonato argénuco. Revisión general de sus técnicas y aplicaciones en histología normal y patológica. Arch Hisi. N y Pat,2:231 y 577,1943
lO- Antanitus DS, Choi BH, Lapham LW: lnimunofluorcscence staining of astrocytes in vitro using antiserurn to glial fibrillar acidic protein. Brain Res, 89:363- 67. 1975
Kleihues P, Burger PC, Scheíthauer BW: 1-listological Typing of Tumours of the Central Nervous System.2° Ed, Springer- Verlag 1993. Rosal J .Ackcrmans Surgical Pathologv. 7° Ed, St LOLUS. The Mosby Co. 1996 Becker LE, Halliday WC: Central nervous system tumors of chi Ihood Perspecto Pediats Pathol, 10:86-134,1987
Wikstrand CJ, Bigner DD: lmmunohiologic aspeets of the brain and humans gliomas. ']'he Ami Pathol, 98:517- 68,1980
Cruz-Sanchez FF, Iglesias IR, Rossi ML, et al: 1-Iistoloeic characterization of 41 ependymomas with the help of a personal coniputerCancer.62: 150-62,1988
Ramon y Cajal S Manual de 1-lislología Normal y (le Técnicas Mi- crogrúticas. 7 Ed, Madrid Imprenta de Nicolá s Noya.192].
Ramon y Cual P Recuerdos de mi vida. Historia (le mi labor científica,4° Ed. Madrid, Alianza Ed, 1984.
HIS W: Veber das Auftreten der weissen substaiiz und der Wurzel Lisen am Ruckenniark (lcr mcnschlichen Emhryonen. Arch E. Anat Physiol. 1 63-170,1883.
Penfield W: Cytolugy and cellular pathology of the nervous sysreni New York, Paul. Hober Inc. 1932.
Del Río 1-Jortega P: Tercera aportación al conocimiento morfológico e interpretación funcional de la oligodendroglia. Arch (le ¡¡¡si N y Pat,6:239-306,1956.
Del Río Hortega P: La neurogl ia normal. Concepto (le neurogliona y angiogliona. Arch de Hist N y Pat,l :5-72,1942.
Kolliker A: Veber Entwicklung der nervenfasern. Anat Anz, 1904. Lumsden CE: Tissue cultLire ni relation to tunlours of the nervous system. ln:
Pathology of lumors of the Nervous Sytem.Russell D, Rubinstein L. London, Arnold Ed, 1963.
Stevenson L, Echlin F: Nature and origin of sorne tumors of the cerebcllum Meduloblastonia. Arch Ncurol Psycli iat 31:93.1934.
ri Polak M. Azcoaga iii: Neuro-histología. Buenos Aires. Ed Eudcba, 1967.
Schaper A: Die fruhesten differen- zierungsvorgangc un] zentral nerven system. Arch II Entwickluns. Vol 5, 1897. Bailey P, Cushing FI: A Ciassification of the Tumors of the Glioma Group on a Histoizenelic Basis with Correlated Studv of Prognosis. Philadelphia,JB
Lippincott, 1926.
(iould VE. Rorke LB. Jansson l)S, el al: Primitive neuroectodermal tumor of the central nervous systeni exprcss neuroendocrme markcrs and may express al ¡ classes of interniediate lilanients. Human Pathol.21 :245-52. 1990.
Rorke LB, Gules EH, Davics RL, Beckcr LE: Revision of dic World Heali Organization Classification of Brain Fumors in Chi ldhood Brain Tuniours.
Cancer 56:1869-86,1985.
Kernohan 1W, Savrc GP: 'lumors of the Central Nervous Systeni.Armcd Forces of Pathology, Washington DC, 1952, Section 10 Fase 35y37.
Zulch K: Brain l'umors. Their Bioloev and Pathology. 2° Ed.I3erhn, N York, Springer-Verlag,1965.
Davies RL, Kepes U. Rorke LB, Vaundenherg SR, Klcihucs P: The art of brain tumor classification. A tribute lo Lucien Rubinstein (1925-1990). Brain Pathol, 1:55-60,1990
Burger PC, Scheithauer 13W: Tumors of the Central nervous sysiem. Atlas of Tumor Pathology. 3° Series, Ese 10, Washington DC, 1994. Arnicd Fo'rces lnstit of Pathol.
Zulch K. Wechsler E.: Pathology and Classircation of Gliomas In: Progress in Neurological Surgery. In: Ycars Book Nedical Publishers Inc. 2° Ed, Chicago. vol 2.1968.
Russcll D. Rubinstein Li: Pathology ofthc Ncrvous System.4° Ed. Baltiniorc, The Wil 1 iams and Wi]kins Co, 1977.
Feigiri Hl. Gross SW: Sarcoma arising ja Glioblastoma of the brain Am .1 Pathol, 3 1:633-53,1955
Polak M, Thomson A: Distribución y características microscópicas del sector conectivo vascular en los tumores del SNC y P: Glioepitelioma, Glioblastoinu Isomorfo. Arch de Hisi N y P, IV. 3:241 -64,1951.
Chow ('VV. Klug GL, Lewis EA: Suhcpendynial giant ccli astrocytonia 111 chi Idren. Aa inusual diserepancy betwcen histological and clinical l'caturcs. .1 Neurosurg .68:880-83,1988.
Kepes Ji,Rubinstein Li, Anshacher L. Schreiber Di: IIistopathological faturcs of recurrcnt pleomorph i e xanthoastro-
cytoina. 1- urther corroborati on of the gl ial nature of this ncoplasm. A study of three cases. Acta Neuropath01.78:585-93. 1989.
Macaulay RJB. lay V. 1 loffmnan 11.1. Bckcr LE: Incrcased mitotic activity as a negative prognostic indicator in pleomorph ic xanthoa stroç vioin a - .1Neurosurg 79:761-68,1993.
Kerriohan 1W, Uihlcin A: Sarcomas of dic Brain. Springfield, Illinois, Charles C Thomas, 1962. Burger PC, Fuller GN:Pathology trcnds
and pitfalls in histologic diagnosis irnirninopathology and applications of oncogcne research. Ncurol Clin, 9 (2): 949-71. 1991.
Fletcher C. DM: Diagnostic H istopatho Iogy of tuni or Ch urc hill Livingstones New York Tomo II. Pag. 1161 1995. Weidner N. The Difficult Diagnosis in Surgical Pathology W. B. Saunders Company Philadclfia USA. pag. $75 1996.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Universidad Nacional de Córdoba
![Creative Commons License](http://i.creativecommons.org/l/by-nc/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The Faculty of Medical Sciences Journal (RFCM) subscribes to the Open Access policy and does not charge authors fees for publishing, nor does it charge readers fees for accessing published articles (APC).