Oral multiple carcinomatosis in a patient from an area with endemic regional chronic hydroarsenicism (erch)
Keywords:
chronic arsenicism, well water, premalignants and maligilants oral lesionsAbstract
Background: Arsenic (As) and its compounds may cause multiple harmful effects on the human organism, interfering with biological processes of vital importance. It is known that the inhabitants of vast areas of the Argentine Republic drink well water contaminated with AS, which results in a disease known as Endemic Regional Chronic Hydroarsenicism (ERCH). It has been observed that these patients present a clinical picture characterized by multiple carcinomatous skin lesions which occur concurrently or successively along long periods of time. Purpose: To present the clinical case of a female patient from the arsenical area of Cordoba Province, who had multiple carcinornatous oral lesions. Materials and method: The patient's history was written and iconographies, surgical excision of the hp lesions, pathological studies of the samples, and evolution observations were done.
Results: Based on both the patient's history and follow-up studies, it was possible to prove the presence of multiple successive carcinomatous lesions in the oral mucosa. Conclusion: It is concluded that drinking water containing more AS than the quantity accepted by the WHO (0.0 5 ppm) can cause multiple carcinomatous lesions on the oral mucosa as well as on the skin.
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