Tomographic characteristics of solid-pseudopapillary neoplasms (Frantz tumor)

Authors

  • Carmen Rosa Cerron-Vela Instituto Nacional de Salud del Niño San Borja. Lima, Perú
  • Percy Moreno Navarro Instituto Nacional de Enfermedades Neoplásicas. Lima, Perú.
  • William J Araujo-Banchon Universidad Continental. Grupo de Investigación Continental; Perú.

DOI:

https://doi.org/10.31053/1853.0605.v77.n1.26228

Keywords:

pancreatic neoplasms, computed tomography, Peru

Abstract

Introduction: Solid-pseudopapillary neoplasms (SPN), or Frantz tumor, is a rare, low-grade neoplasm that occurs mainly in young women. It was described in 1959 by Virginia Frantz and constitutes 0.2-2.7 % of all pancreatic tumors. Computed tomography (CT) plays an important role in the diagnosis of this pathology of scarce reporting. The objective of the present study is to describe the epidemiological and tomographic characteristics of the SPN in the Instituto Nacional de Enfermedades Neoplásicas (INEN) of Peru. Methods: Descriptive cross-sectional study performed with medical records of all patients diagnosed with SPN between 2004 and 2014. The variables described were tumor size, location, shape, borders, thickness of the capsule, composition, calcifications and uptake of contrast. The categorical variables were expressed in absolute and relative frequencies; while the numerical variables were described with median and interquartile deviation (ID). Statistical support STATA Version 12.0 was used. Results: Of all pancreatic cystic tumors (PCT), 51.9% corresponded to confirmed cases of TSP. The median age was 23.5 years. The isolated location in the head predominated (33.3%); the most frequent mixed location was body and tail (16.7%); diameter was more frequent between 5.1-10 cm and the content of the majority was predominantly solid. 30.0% of the NSP presented calcifications. Aim conclusion: Most cases of INP SPN (2004-2014) have similar characteristics to those reported in the international literature.

Downloads

Download data is not yet available.

References

Frantz V. Papillary tumors of the pancreas: benign or malignant. In: Atlas of tumor pathology. Section 7, fascicles 27 and 28. 1st ed. Washington, DC, USA: Armed Forces Institute of Pathology; 1959. 32-3 p.

El Nakeeb A, Abdel Wahab M, Elkashef WF, Azer M, Kandil T. Solid pseudopapillary tumour of the pancreas: Incidence, prognosis and outcome of surgery (single center experience). Int J Surg. 2013;11(6):447-57. doi: 10.1016/j.ijsu.2013.04.009.

Klöppel G. Histological typing of tumours of the exocrine pancreas. Berlin: Springer; 1998.

Raffel A, Cupisti K, Krausch M, Braunstein S, Tröbs B, Goretzki PE, Willnow U. Therapeutic strategy of papillary cystic and solid neoplasm (PCSN): a rare non-endocrine tumor of the pancreas in children. Surgical Oncology. 2004 Jul 1;13(1):1–6.

Słowik-Moczydłowska Ż, Gogolewski M, Yaqoub S, Piotrowska A, Kamiński A. Solid pseudopapillary tumor of the pancreas (Frantz's tumor): two case reports and a review of the literature. J Med Case Rep. 2015 Nov 20;9:268. doi: 10.1186/s13256-015-0752-z. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653910/

Abad Licham M, Sanchez Lihon J, Celis Zapata J. Tumor sólido pseudopapilar de páncreas en el Instituto Nacional de Enfermedades Neoplásicas. Revista de Gastroenterología del Perú. 2008 Oct;28(4):356–361. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_abstract&pid=S1022-51292008000400004&lng=es&nrm=iso&tlng=en

Instituto Nacional de Salud. Aprobación y publicación de prioridades Nacionales de Investigación 2016-2021 [Internet]. 2016. Disponible en: https://web.ins.gob.pe/sites/default/files/Archivos/ogitt/prioridades/5a%20Prioridades%20Nacionales%20de%20Investigaci%C3%B3n.pdf

Park MJ, Lee JH, Kim JK, Kim YC, Park MS, Yu JS, Kim YB, Lee D. Multidetector CT imaging features of solid pseudopapillary tumours of the pancreas in male patients: distinctive imaging features with female patients. Br J Radiol. 2014 Mar;87(1035):20130513. doi: 10.1259/bjr.20130513. Epub 2014 Feb 3.

Cerdán P R, Barranco D JI, Cantín B S, Bernal J J, Serrablo R A, Esarte M JM. Tumor de Frantz: Presentación de un caso. Revista chilena de cirugía. 2007 Apr;59(2):145–149. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_abstract&pid=S0718-40262007000200012&lng=es&nrm=iso&tlng=es.

Machado MC, Machado MA, Bacchella T, Jukemura J, Almeida JL, Cunha JE. Solid pseudopapillary neoplasm of the pancreas: distinct patterns of onset, diagnosis, and prognosis for male versus female patients. Surgery. 2008 Jan;143(1):29-34. doi: 10.1016/j.surg.2007.07.030.

Klöppel, G, Solcia, E, Longnecker, D. S, Capella, C, Sobin, Leslie H. et al. Histological typing of tumours of the exocrine páncreas. Springer; 1996 Disponible en: https://ci.nii.ac.jp/naid/10024156538/

Llatas J, Palomino A, Frisancho O. Tumor de Frantz: neoplasia sólida pseudopapilar de páncreas. Revista de Gastroenterología del Perú. 2011 Jan;31(1):56–60. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_abstract&pid=S1022-51292011000100010&lng=es&nrm=iso&tlng=es

Choi SH, Kim SM, Oh JT, Park JY, Seo JM, Lee SK. Solid pseudopapillary tumor of the pancreas: a multicenter study of 23 pediatric cases. J Pediatr Surg. 2006 Dec;41(12):1992-5. doi: 10.1016/j.jpedsurg.2006.08.024.

Cantisani V, Mortele KJ, Levy A, Glickman JN, Ricci P, Passariello R, Ros PR, Silverman SG. MR Imaging Features of Solid Pseudopapillary Tumor of the Pancreas in Adult and Pediatric Patients. American Journal of Roentgenology. 2003 Aug 1;181(2):395–401.

Yu PF, Hu ZH, Wang XB, Guo JM, Cheng XD, Zhang YL, Xu Q. Solid pseudopapillary tumor of the pancreas: a review of 553 cases in Chinese literature. World J Gastroenterol. 2010 Mar 14;16(10):1209-14. doi: 10.3748/wjg.v16.i10.1209. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839172/

Roggin KK, Chennat J, Oto A, Noffsinger A, Briggs A, Matthews JB. Pancreatic Cystic Neoplasm. Current Problems in Surgery. 2010 Jun 1;47(6):459–510.

Published

2020-03-16

How to Cite

1.
Cerron-Vela CR, Moreno Navarro P, Araujo-Banchon WJ. Tomographic characteristics of solid-pseudopapillary neoplasms (Frantz tumor). Rev Fac Cien Med Univ Nac Cordoba [Internet]. 2020 Mar. 16 [cited 2024 Jun. 26];77(1):33-8. Available from: https://revistas.unc.edu.ar/index.php/med/article/view/26228

Issue

Section

Original Papers