Ischemic stroke related to COVID-19: integral revision

Authors

  • Kevyn Felipe Mendes Universidad Internacional de las tres fronteras
  • Mirela Pereira Lima Abrão Universidade Federal de Goiás
  • Marcos Arturo Ferreira Agüero Universidad Internacional Tres Fronteras -Facultad de Ciencias de la Salud
  • Isadora Pereira Brito Universidade De Rio Verde - Campus Aparecida de Goiânia
  • Grecia Silva Melo Universidade de Rio Verde - Campus Aparecida de Goiania
  • Leonardo Vicari Santos IMED- Passo Fundo
  • Ana Claudia Mendes Barbosa Centro Universitario Varzea Grande - Mato Grosso

DOI:

https://doi.org/10.31052/1853.1180.v28.n2.38111

Keywords:

2019 Novel Coronavirus Disease, cardiovascular diseases, COVID-19 pandemic

Abstract

Introduction: The human respiratory system is the main target of COVID-19; however, it also has neuro-invasive abilities. The hypercoagulable condition caused by the infection is one of the main risk factors for an ischemic stroke. Despite its low incidence, it has high morbidity and mortality, increased even more when associated with risks factors which may favor such is occurrence.  

Materials and methods: This study is an integral revision of literature, at three data bases. PubMed, Scielo and Lilacs, with studies from 2019-2021. Inclusion criteria were: original articles in English or Portuguese; patients with high blood pressure (HBP) and/or diabetes as risk factors, or no comorbidities. Exclusion criteria were: original articles in incompatible languages; no evaluated risk factors or no relevant for the topic.

Results: Out of 24 patients with ischemic stroke related to COVID-19 who were evaluated, 70.83% were men and 35.29% were over 64 years old. Diabetes was more prevalent in women (60%) and HBP in men (75%). Regarding evolution, 41.17% of the patients died; 57.14 of them presented HBP.

Conclusions: This study showed the relationship between risk factors and patients’ age range regarding the occurrence of ischemic stroke related to COVID-19. Although age is a determinant factor in ischemic strokes, comorbidities showed significant importance.

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Author Biographies

Mirela Pereira Lima Abrão, Universidade Federal de Goiás

Mestranda no Progr ama de Pós Graduação em Ciências da Saúde pela Faculdade de Medicina da Universidade Federal de Goiás ( UFG)

Marcos Arturo Ferreira Agüero, Universidad Internacional Tres Fronteras -Facultad de Ciencias de la Salud

Professor Phd

Isadora Pereira Brito, Universidade De Rio Verde - Campus Aparecida de Goiânia

Acadêmica de medicina

Grecia Silva Melo, Universidade de Rio Verde - Campus Aparecida de Goiania

Acadêmica de Medicina

Leonardo Vicari Santos, IMED- Passo Fundo

Acadêmico de Medicina

Ana Claudia Mendes Barbosa, Centro Universitario Varzea Grande - Mato Grosso

Acadêmica de Medicina

References

Parsay S, Vosoughi A, Khabbaz A, Sadigh-Eteghad S. The Incidence and Mortality Ratio of Ischemic Cerebrovascular Accidents in COVID-19 Cases: A Systematic Review and Meta-Analysis. J Stroke Cerebrovasc Dis. 2021;30(3).

Organization WH. WHO Coronavirus (COVID-19) Dashboard [Internet]. 2021 [cited 2021 Jul 25]. Available from: https://covid19.who.int/

Georgios Tsivgoulis, Lina Palaiodimou AHK, Valeria Caso, Martin Köhrmann, Carlos Molina, Charlotte Cordonnier UF, Peter Kelly, Vijay K. Sharma, Amanda C. Chan, Ramin Zand AS, Peter D. Schellinger, Konstantinos I. Voumvourakis NG, Tsiodras AVA and S. Neurological manifestations and implications of COVID-19 pandemic Georgios. Ther Adv Vaccines. 2020;13(6):259–61.

Trejo Gabriel y Galán JM. Stroke as a complication and prognostic factor of COVID-19. Neurol (English Ed. 2020;35(5):318–22.

Triches C, Schaan BD, Gross JL, Azevedo MJ de. Complicações macrovasculares do diabetes melito: peculiaridades clínicas, de diagnóstico e manejo. Arq Bras Endocrinol Metabol. 2009;53(6):698–708.

Andersen, K. G., Rambaut, A., Lipkin, W. I., Holmes, E. C., Garry RF. The COVID-19 coronavirus epidemic has a natural origin, scientists say. Nat Med. 2020;26(4):450–2.

Lima CFC, Holanda JLB, Pessoa MSL, Coimbra PP de A. Acute ischemic stroke in a patient with COVID-19. Arq Neuropsiquiatr. 2020;78(7):454–555.

TUNÇ A, ÜNLÜBAŞ Y, ALEMDAR M, AKYÜZ E. Coexistence of COVID-19 and acute ischemic stroke report of four cases. J Clin Neurosci. 2020;77:227–9.

Achebe I, Nagubadi S, Pierre-Louis SJC. Massive Ischemic Strokes in a Young Patient With Severe Coronavirus Disease 2019 Pneumonia. J Investig Med High Impact Case Reports. 2021;9:232470962110283.

Khan AW, Ullah I, Khan KS. Ischemic stroke leading to bilateral vision loss in COVID-19 patient—A rare case report. J Med Virol. 2021;93(2):683–5.

Sousa GC, Sousa TC, Sakiyama MAK, Silva JSNL SE. Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report. J Clin Neurosci. 2020;79:169–71.

De Almeida Lima AN, Santos Leite Pessoa M, Franco Costa Lima C, Picasso de Araújo Coimbra P, Bezerra Holanda JL. Images in Vascular Medicine: Acute peripheral artery occlusion and ischemic stroke in a patient with COVID-19. Vasc Med (United Kingdom). 2020;25(5):482–3.

Diaz-Segarra N, Edmond A, Kunac A, Yonclas P. COVID-19 Ischemic Strokes as an Emerging Rehabilitation Population: A Case Series. Am J Phys Med Rehabil. 2020;99(10):876–9.

Popov AF, Berger R, Schlensak C, Bongers MN, Haeberle H, Acharya M, et al. Mechanical circulatory support for cardiovascular complications in a young COVID-19 patient. J Card Surg. 2020;35(11):3173–5.

Rudilosso S, Esteller D, Urra X, Chamorro Á. Thalamic perforating artery stroke on computed tomography perfusion in a patient with coronavirus disease 2019. J Stroke Cerebrovasc Dis. 2020;29(8):337–9.

Valderrama EV, Humbert K, Lord A, Frontera J, Yaghi S. Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Ischemic Stroke. Stroke. 2020;(July):E124–7.

Priftis K, Algeri L, Villella S, Spada MS. COVID-19 presenting with agraphia and conduction aphasia in a patient with left-hemisphere ischemic stroke. Neurol Sci. 2020;3–6.

Frisullo G, Bellavia S, Scala I, Piano C, Morosetti R, Brunetti V, et al. Stroke and COVID19 : Not only a large-vessel disease. 2020;29(10):1–2.

Mansour OY, Malik AM, Linfante I. Mechanical Thrombectomy of COVID-19 positive acute ischemic stroke patient: a case report and call for preparedness. BMC Neurol. 2020;20(1):358.

Iqbal P, Laswi B, Jamshaid MB, Shahzad A, Chaudhry HS, Khan D, et al. The role of anticoagulation in post-COVID-19 concomitant stroke, myocardial infarction, and left ventricular thrombus: A case report. Am J Case Rep. 2021;22(1):1–6.

Robles LA. Bilateral Large Vessel Occlusion Causing Massive Ischemic Stroke in a COVID-19 Patient. J Stroke Cerebrovasc Dis. 2021;30(January).

Aasfara J, Jidane S, Laarje A, Yamani K El, Belyamani L, Tijani Y. SARS-CoV-2, recurrent ischemic strokes and carotid macrothrombosis: The other face of the cytokine storm (a case report). Pan Afr Med J. 2021;38:1–5.

Brem FL, Abu-Al-tayef T, Rasras H, Mir Z El, Mahi O El, Ouafi N El. Concomitant acute limb ischemia and multiple acute ischemic strokes complicating covid-19: A case report. Pan Afr Med J. 2021;38.

Mowla A, Sizdahkhani S, Sharifian-Dorche M, Selvan P, Emanuel BA, Tenser MS, et al. Unusual Pattern of Arterial Macrothrombosis Causing Stroke in a Young Adult Recovered from COVID-19. J Stroke Cerebrovasc Dis. 2020;29(12):1–5.

Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, et al. Neurologic Manifestations of Hospitalized Patients with Coronavirus Disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683–90.

Hess DC, Eldahshan W, Rutkowski E. COVID-19-Related Stroke. Transl Stroke Res. 2020;11(3):322–5.

Bhatia R SM. COVID-19 and Stroke: Incidental, Triggered or Causative. Ann Indian Acad Neurol. 2020;23(3):318–324.

Square Q. Characteristics of ischaemic stroke associated with COVID-19. J Neurol Neurosurg Psychiatry. 2020;91(8):889–891.

Sociedade Brasileira de Doenças Cerebrovasculares. ACIDENTE VASCULAR CEREBRAL [Internet]. 2021 [cited 2021 Jul 25]. Available from: http://www.sbdcv.org.br/publica_avc.asp

Published

2023-01-05

How to Cite

1.
Felipe Mendes K, Pereira Lima Abrão M, Arturo Ferreira Agüero M, Pereira Brito I, Silva Melo G, Vicari Santos L, Mendes Barbosa AC. Ischemic stroke related to COVID-19: integral revision. Rev. Salud Pública (Córdoba) [Internet]. 2023 Jan. 5 [cited 2024 Jul. 6];28(2). Available from: https://revistas.unc.edu.ar/index.php/RSD/article/view/38111

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