Dyslipidemia in patients with HIV
DOI:
https://doi.org/10.31052/1853.1180.v18.n3.11733Keywords:
Human Immunodeficiency Virus HIV – Acquired immunodeficiency syndrome. Antiretroviral therapy. DyslipidemiasAbstract
Abstract Since the introduction of highly active antiretroviral therapy (ART) in the treatment of HIV/AIDS patients, we have observed a change in the development of the disease, becoming a chronic therapeutically containable condition. The increase in survival goes together with associated diseases; cardiovascular ones have become relevant, being earlier and more severe. Dyslipidemias have a leading role in this pathology. In this work, we analyze their incidence and characteristics in HIV patients, with and without ART treatment. Lipid profile was different in the pre-treatment stage (low HDL, low total Cholesterol and normal TG) from the stage under ART (marked increase of TG and to a lesser extent of total Cholesterol and LDL), with a significant association of the use of Protease Inhibitors (PIs) and CD4 levels lower than 200/mm3.
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