Problemas Relacionados al Alcohol: Bases Neurobiológicas del consumo de alcohol y Modelos Animales desarrollados para el abordaje de estas problemáticas

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Samanta M. March
Roberto Sebastián Miranda Morales

Resumen

El presente trabajo se centra en los modelos animales desarrollados para el abordaje del uso, abuso y dependencia de alcohol. Estos modelos han permitido el abordaje de diversas aristas vinculadas con la ingesta de alcohol, desde las disposiciones genéticas hasta los efectos de la exposición a la droga durante el desarrollo. También han permitido la evaluación de la eficacia de tratamientos farmacológicos y de los fenómenos asociados con el abuso de la droga, como el deseo incontrolable (craving), tolerancia y recaída. El articulo comienza con una breve reseña de las bases neurobiológicas del reforzamiento etílico, principalmente el rol del sistema opiáceo. De allí se abordan diferentes modelos, se describen modelos centrados en las bases genéticas, luego se describen modelos vinculados al estudio de fenómenos específicos observados en personas con desórdenes relacionados al uso de alcohol y finalmente modelos que subrayan cómo las experiencias tempranas con la droga pueden predisponer a un consumo problemático etapas posteriores de la vida.

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March, S. M., & Miranda Morales, R. S. (2009). Problemas Relacionados al Alcohol: Bases Neurobiológicas del consumo de alcohol y Modelos Animales desarrollados para el abordaje de estas problemáticas. Revista Argentina De Ciencias Del Comportamiento, 1(1), 36–50. https://doi.org/10.32348/1852.4206.v1.n1.5302
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Biografía del autor/a

Samanta M. March, Instituto Ferreyra

Facultad de Psicología, Universidad Nacional de Córdoba, Córdoba, Argentina.

Roberto Sebastián Miranda Morales, Instituto Ferreyra

Facultad de Psicología, Universidad Nacional de Córdoba, Córdoba, Argentina.

Citas

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