Persistência de IgM SARS-COV-2 em pacientes que completaram quarentena para COVID-19, em Arequipa, Peru
DOI:
https://doi.org/10.31052/1853.1180.v29.n1.32051Palavras-chave:
Infecções por coronavírus, sorologia, imunoglobulina M, reações de falso positivo, doenças autoimunes, fator reumatóideResumo
Objetivo: Analisar as características clínicas de pacientes convalescentes para COVID-19, que apresentam persistência de IgM.
Material e métodos: Estudo analítico. Foram avaliados 614 pacientes, do dia 21 ao 175 após o início dos sintomas. Houve 19 casos com IgM positivo (3,1%). Um grupo controle foi utilizado para comparar as variáveis clínicas, agrupando-as por categorias e aplicando o teste Xi-quadrado ou exato de Fisher (p<0,05).
Resultados: A partir do final da quarentena (dia 21), foram registrados casos positivos de IgM, atingindo o maior número no intervalo de 44-65 dias (42,1%). Evidenciou-se associação entre a presença de IgM positiva e doenças autoimunes (p=0,02).
Conclusões: Há persistência de positividade para IgM SARS-CoV-2 até 175 dias após o início dos sintomas, principalmente associada à reação cruzada com doenças autoimunes. Fornecem-se informações úteis para esclarecer as causas e auxiliar no tratamento médico.
Palavras-chave: infecções por coronavírus; sorologia; imunoglobulina M, reações falso-positivas; doenças autoimunes.
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