Etiological profile and antimicrobial sensitivity in community urinary infections in a Private Center in the city of Córdoba
Keywords:
Urinary Tract Infections, Microbial Sensitivity Tests, Community-Acquired InfectionsAbstract
ABSTRACT
Introduction: Urinary Tract Infection is still one of the most frequent infectious entities in our institution; however its incidence has changed over the last decade. The objective of this study is to determine which are the microorganisms responsible for urinary infection in the community and what is the prevalence of antimicrobial resistance of said uropathogens, in order to establish the appropriate empiric treatment in our institution. Materials and methods: Descriptive, retrospective, cross-sectional study of outpatients with a first episode of UTI registered at Sanatorio Allende in the city of Córdoba, Argentina from January 2016 to December 2017. There were 1740 analyzed urine cultures which met the inclusion criteria. The 90,2% (n=1570) of the analyzed total are female. Escherichia coli was the most frequently isolated microorganism (80,3%), followed by Staphylococcus saprophyticus (8,0%), Klebsiella pneumoniae (4,1%), Enterococcus faecalis (3%), Proteus mirabilis (2,3%), and others (2,1%). Out of 1740 isolations, 47,6% were resistant to ampicillin, 29,6% to sulfamethoxazole trimethoprim, 15,2% to ciprofloxacin, 4,6% to first-generation cephalosporins, 3,4% to cefixime, 2,3% to amoxicillin clavulanic, 1,2% to Gentamicin and 1% to Nitrofurantoin. Conclusion: This study shows higher prevalence of Escherichia coli with high rates of resistance to ampicillin, treatments and fluoroquinolones. Thus, it is important to identify and characterize the microorganisms and sensitivity profiles to antimicrobials in order to be able to define critically which much be the top-of-the-line antibiotics chosen for an empiric treatment.
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