CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES

Authors

  • Lucrecia Marks HOSPITAL DE NIÑOS DE LA SANTISIMA TRINIDAD.
  • Ines Isabel Gonzalez Laboratorio Toxicologia Hospital de Niños de la Santisima Trindidad
  • Hector Andres Suarez Laboratorio Toxicologia Hospital de Niños de la Santisima Trindidad
  • Susana Elvira Rivolta Laboratorio General y de Especialidades Hospital de NIños de la Santisima Trinidad

DOI:

https://doi.org/10.31052/1853.1180.v23.n3.21974

Keywords:

benzodiazepine metabolites, concordance, immunological tests

Abstract

Due to the great number of commercial tests available in the market to determine urinary benzodiazepine metabolites, we decided to assess the concordance between two immunological tests available in the Toxicology lab in our hospital. Urine samples received in our lab were analyzed by both methods at the same time. Statistics tests of Kappa and Chi-Square are used for evaluation. The usefulness of these tests in cases of the diagnostic suspicion of benzodiazepine consumption in certain pathologies deserves the availability of these immunological tests since they can provide results in a short time which will let the medical professional make timely decisions regarding the problem presented by the patient. In this work we have been able to verify that both methods show good concordance (Kappa Test = 0.88) so, both can be indistinctly used for the cases presented by the Toxicology lab.

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Author Biographies

  • Lucrecia Marks, HOSPITAL DE NIÑOS DE LA SANTISIMA TRINIDAD.

    Lic. en Bioquimica clinica, Jefa de Residentes. laboratorio de Toxicología. Hospital de Niños de la Santisima Trinidad.

    Alumna de la Esp. en Toxicología Clínica

  • Ines Isabel Gonzalez, Laboratorio Toxicologia Hospital de Niños de la Santisima Trindidad

    Bioq. Esp. en Toxicología y Bioq. Legal.

    Farmaceutica.

  • Hector Andres Suarez, Laboratorio Toxicologia Hospital de Niños de la Santisima Trindidad
    Lic. en Bioq. Clinica Esp. en Toxicología y Bioq. Legal
  • Susana Elvira Rivolta, Laboratorio General y de Especialidades Hospital de NIños de la Santisima Trinidad

    Jefa del Dpto Diagnostico del Hospital de Niños de la Santisima Trinidad.

    Bioq. Clinica

    Mg Salud Publica

    Mg Adiccion y Prevencion de drogas de abuso.

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Published

2019-12-03

Issue

Vol. 23 No. 3 (2019): Revista de Salud Pública

Section

Brief Communications

License

Copyright (c) 2019 Escuela de Salud Pública y Ambiente. Facultad de Ciencias Médicas. Universidad Nacional de Córdoba

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How to Cite

1.
CONCORDANCE OF TWO IMMUNOLOGICAL METHODS TO DETERMINE URINARY BENZODIAZEPINE METABOLITES . Rev. Salud Pública (Córdoba) [Internet]. 2019 Dec. 3 [cited 2024 Oct. 19];23(3):77-84. Available from: https://revistas.unc.edu.ar/index.php/RSD/article/view/21974