Evolución morfohistoquimica del mesenquima en glándulas labiales fetales humanas

Abstract

The structural and histochemical patterns of the salivary mesenchyma were analysed in relation to the epithelium of the labial glands during the embryonic development to correlata the structural and histochemical characteristics in both tissues during the histogenesis. Samples of h~man fetal lips were analysed using H/E, PAS, Casen, Alcian blue, Tolui dine blue and Methenamine/silver, The process of glandular histogenesis begun between B te 10 weeks. The mesenchy~a surrounding the glandular buds had PAS positiva granulations which were also alcianophilic, met~chromatic and periodatoreactive. Periodatoreactive collagenous fibrillae, reticular cells and nervous fibers of considerable diameter were observad. Basement _membranas were PAS positiva, alcianophilic and di~continu.ous, At 12 weeks the mesenchyma differentiated as loase conne~tive tissue which produced a delicate periglandular capsule with fibra blast and collagenous fibrillae. Froin 20 to 2q weeks ·the ac1n1 wer-¡;;structurally and histochemically differentiated as serous, mucous and mixed, It was postulated that the periglandular mesenchyma would play and important role in the morphogenetic process in relation to the hist~chemical identification of molecules which have a specific biological functions in the epithelium-mesenchyma interactions during organogenesis