Characterization of lithiasis in minor salivary glands: cases report and revision of a rare phenomenon

Authors

  • Juan Cruz Romero Panico

Keywords:

sialolithiasis, report case, diagnosis

Abstract

Sialolithiasis is a relatively common condition, affecting the major salivary gland ducts with a higher incidence. The finding of sialoliths in minor salivary glands is extremely rare. Some of the reasons that would indicate the limited scientific evidence surrounding the diagnosis of minor salivary gland sialolithiasis could be associated with an underdiagnosis of the pathology, and the absence of histopathological diagnosis after surgical excision. Objective: two cases are presented, in adult patients, with clinical and histopathological diagnosis of sialolithiasis in minor salivary glands, who attended the Outpatient Clinic of the Chair of Stomatology A, of the Faculty of Dentistry, of the National University of Córdoba, in the period 2021-2022. Additionally, a narrative review of some of the possible etiological aspects of this phenomenon is provided. It is important to report these cases to generate greater scientific evidence about this entity and, in this way, achieve a better understanding of it, expand the range of differential diagnoses and therapeutic options for this pathology

References

1. Pullon, P. A. & Miller, A. S. Sialolithiasis of accessory salivary glands: review of 55 cases. J Oral Surg 30, 832–834 (1972).

2. van der Waal, I. Sialolithiasis of minor salivary glands: how rare? Report of two cases. J Oral Surg 29, 815–816 (1971).

3. Matiakis, A. & Tzermpos, F. Sialolithiasis of minor salivary gland: a challenging diagnostic dilemma. J Korean Assoc Oral Maxillofac Surg 47, 145–148 (2021).

4. Ben Lagha, N., Alantar, A., Samson, J., Chapireau, D. & Maman, L. Lithiasis of minor salivary glands: current data. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100, 345–348 (2005).

5. Alcure, M. L., Della Coletta, R., Graner, E., Di Hipolito, O. & Lopes, M. A. Sialolithiasis of minor salivary glands: a clinical and histopathological study. Gen Dent 53, 278–281 (2005).

6. Stanley, M. W., Bardales, R. H., Beneke, J., Korourian, S. & Stern, S. J. Sialolithiasis. Differential diagnostic problems in fine-needle aspiration cytology. Am J Clin Pathol 106, 229–233 (1996).

7. Takeda, Y., Oikawa, Y., Satoh, M. & Nakamura, S. Sialolith of the submandibular gland with bone formation. Pathol Int 53, 309–312 (2003).

8. Seifert, G., Miehike, A., Haubrich, J., Chilla, R. & Stuttgart, G. Diseases of the Salivary Glands, Pathology – Diagnosis – Treatment. (1986).

9. Anneroth, G. & Hansen, L. S. Minor salivary gland calculi. A clinical and histopathological study of 49 cases. Int J Oral Surg 12, 80–89 (1983).

10. Pinheiro, T. N. et al. Giant sialolith associated with Actinomyces infection, suggesting a new etiopathogenic correlation: a case report. Gen Dent 69, 29–33 (2021).

11. Anneroth, G., Eneroth, C. M. & Isacsson, G. Morphology of salivary calculi. The distribution of the inorganic component. J Oral Pathol 4, 257–265 (1975).

12. Riesco, J. M. et al. Crystalloid architecture of a sialolith in a minor salivary gland. Journal of Oral Pathology & Medicine 28, 451–455 (1999).

13. Wang, W.-C. et al. Sialolithiasis of minor salivary glands: A review of 17 cases. J Dent Sci 11, 152–155 (2016).

14. Pettas, E. et al. Canalicular adenoma with unicystic morphology. A rare entity. J Clin Exp Dent 13, e88–e94 (2021).

15. Touati, M. M. & Lakouichmi, M. About a rare tumor of the upper lip: the mucoepidermoid carcinoma. Pan Afr Med J 22, 39 (2015).

16. Prakash, A. J., Christina, S. S., Lakshmi, M. V. & Polishetty, N. Basal cell adenocarcinoma of the minor salivary gland - A rare case report involving the upper lip. J Cancer Res Ther 18, 765–769 (2022).

17. Lee, L.-T. & Wong, Y. K. D. Pathogenesis and diverse histologic findings of sialolithiasis in minor salivary glands. J Oral Maxillofac Surg 68, 465–470 (2010).

18. Abe, A., Kurita, K., Hayashi, H. & Minagawa, M. A case of minor salivary gland sialolithiasis of the upper lip. Oral Maxillofac Surg 23, 91–94 (2019).

19. Panico, R., Panico, I., Leonardi, N., Garola, F. & Gilligan, G. An unexpected finding in a labial swelling. Oral Surg Oral Med Oral Pathol Oral Radiol 133, 259–263 (2022).

Published

2023-12-05