Pulp regeneration: from stem cells to exosomes

Authors

  • Viviana Centeno Universidad Nacional de Córdoba, Facultad de Odontología, Departamento de Biología Bucal

Keywords:

stem cells, exosome

Abstract

The search for new tools in regenerative dentistry is of extreme importance and the knowledge acquired will offer the opportunity to renew the classic clinical procedures by innovative methodologies that cross the current borders in oral health care.

References

Tatullo M, Codispoti B, Paduano F, Nuzzolese M. and Makeeva I. Strategic Tools in Regenerative and Translational Dentistry. Int J Mol Sci. 2019; 20:1879-1893.

2. Nicoloso GF, Goldenfum GM, Pizzol TDSD, Scarparo RK, Montagner F, de Almeida Rodrigues J, Casagrande L. Pulp Revascularization or Apexification for the Treatment of Immature Necrotic Permanent Teeth: Systematic Review and Meta-Analysis. J Clin Pediatr Dent. 2019; 43(5):305-313.

3. Cheng J, Jiang G, Tarzemany R, Larjava H, Häkkinen L. Regulation of connexin 43 expression in human gingival fibroblasts. Exp Cell Res. 2018; 371(1):238-249.

4. Li S, He H, Zhang G, Wang F, Zhang P,Tan Y. Connexin43-containing gap junctions potentiate extracellular Ca²⁺-induced odontoblastic differentiation of human dental pulp stem cells via Erk1/2. Exp Cell Res.2015; 338(1):1-9.

5. Wiklander OP, Nordin JZ, O’Loughlin A, Gustafsson Y, Corso G, Mäger I, , Vader P, Yi L, Sork H, Seow Y, Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting. J. Extracell Vesicles 2015; 4: 26316-23329.

Published

2019-12-20