Since genes to clinical care-buccal oncology-

Authors

  • Mabel Brunotto

Keywords:

genética, oncología, cavidad bucal

Abstract

The prevention of cancer is one of the best strategies at the Public Health level since it is a low cost method and highly effective over time. Early detection allows intervention in the early stages of the disease, this being a moment with high potential to achieve healing. The evaluation of diagnostic indicators, such as symptoms and genetic tests, allows increasing the sensitivity and specificity of the determination of the presence / absence of a malignant pathology. A description of profiles of biomarkers in relation to changes in the profiles of these markers at different times allows us to assess, for example, the progression towards malignization of patients with premalignant lesions.

Author Biography

  • Mabel Brunotto

    Universidad Nacional de Córdoba, Facultad de Odontología, Dpto Biología Bucal.

    Instituto de Investigaciones en Ciencias de la Salud INICSA-CONICET-UNC

     

References

Giovanella L,Feo O, Faria M, Tobar S (orgs.).Sistemas de salud en Suramérica: desafíos para launiversalidad la integralidad y la equidad / InstitutoSuramericano de Gobierno en Salud; Rio de Janeiro: ISAGS, 2012. Disponible en:http://www.slideshare.net/isagsunasur/sistemas-de-salud-en-suramerica.

Lingen MW, Pinto A, Mendes RA, Franchini R, Czerninski R, Tilakaratne WM, et al. Genetics/epigenetics of oral premalignancy: current status and future research. Oral Dis.2011; 17:7-22

Zarate AM, BrezzoMM, Secchi DG, Barra JL, BrunottoM. Malignancy Risk Models for Oral Lesions. Med Oral Patol Oral Cir Bucal. 2013. doi:10.4317/medoral.18374.

Vukovic V, Stojanovic J, Vecchioni A, Pastorino R, Boccia S. Systematic Review and Meta-analysis of SNPs from Genome-Wide Association Studies of Head and Neck Cancer. Otolaryngol Head Neck Surg. 2018; 159(4):615-624. doi: 10.1177/0194599818792262

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Published

2018-12-19

Issue

Section

Editorial