Sustratos neuroanatómicos y funcionales del córtex prefrontal medial

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Jorge Alexander Ríos Flórez

Resumen

Este artículo se presenta como una revisión que buscó integrar el conocimiento actualizado que se tiene sobre los sustratos neuroanatómicos y morfológicos de los circuitos funcionales que el córtex prefrontal medial (mPFC) establece con otras estructuras cerebrales. Diversas investigaciones han descrito las proyecciones emergentes y/o convergentes del mPFC, principalmente tomando como modelo de estudio a los roedores; empleándose la técnica de marcador neuronal como principal técnica de indagación de tales proyecciones, seguido de trabajos que proponen electrofisiografía para develar la conectividad cerebral. Así, se ha descrito la interacción del mPFC con otras estructuras encefálicas, entre las que se destacan principalmente el hipocampo, la sustancia gris periacueductal, el hipotálamo, el núcleo accumbens, la amígdala cerebral, el área tegmental ventral, el núcleo dorsal de Rafe y la habénula lateral del epitálamo, entre otras. Estas investigaciones han ido más allá del componente físico de la conectividad encefálica, extrapolando y posibilitando la comprensión funcional de las vías anatómicas establecidas entre las diferentes regiones interrelacionadas con el mPFC, develando la actividad cognitivo-comportamental de los sujetos de estudio.

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Ríos Flórez, J. A. (2019). Sustratos neuroanatómicos y funcionales del córtex prefrontal medial. Revista Argentina De Ciencias Del Comportamiento, 10(3), 43–53. https://doi.org/10.32348/1852.4206.v10.n3.20619
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Jorge Alexander Ríos Flórez, Universidade Federal do Rio Grande do Norte. Grupo de Investigación en Neurociencias Hippocampus

Docente-Investigador. Director del Grupo de Investigación en Neurociencias Hippocampus; Psicólogo, Universidad Pontificia Bolivariana, Especialista en Evaluación y Diagnóstico Neuropsicológico, Magíster en Neuropsicología clínica, Universidad de San Buenaventura, Bogotá, D.C., Colombia. Miembro del Grupo Psicología, Educación y Cultura de la Institución Universitaria Politécnico Grancolombiano. Doctorando en Psicobiología, Universidade Federal do Rio Grande do Norte, Brasil.

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