Keywords
neuroimmunoendocrineinteractions
metabolism
How to Cite
Abstract
The article refers to the various mechanisms that trigger the inflammatory response and the consequences that usually occur when the noxious agent is not cleared leading to the perpetuation of the process, which is linked to the interconnection between the major systems of the body: immune, endocrine and the autonomic nervous system. In line with the most recent research, a new approach is also offered where inflammation becomes a response aimed at restoring homeostasis. One facet deals with excessive deviations of cellular processes, unable to be controlled by regulatory mechanisms, which has some, but not all the features of the classic response, namely para or metaflammation. On the other hand, the traditional inflammation, which, although it may be related to this phenomenon, is particularly linked to the response to pathogens, toxins, or other agents that cannot be regulated, but are equally life-threatening.
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